Question 1

Glycogen synthase is converted into the active form by the action of _________________.

Accepted Answer

protein ph...

Question 2

What is the function of liver glycogen degradation?

Accepted Answer

A)   For glucose export to other tissues when glucose levels are low
B)   To maintain glucose levels after a large meal
C)   To provide for the large energy needs of the liver
D)   To allow for synthesis of lipids
E)   None of the answers is correct.F) A) and E)
G) B) and C)

Question 3

Why does liver possess a specific enzyme that can cleave glucose 6-phosphate to form glucose and orthophosphate?

Accepted Answer

The liver controls the blood g...

Question 4

What reaction cleaves a bond by the addition of orthophosphate?

Accepted Answer

A)   phosphorolysis
B)   phosphatase
C)   transphosphorylation
D)   oxidative phosphorylation
E)   None of the answers is correct.F) B) and E)
G) A) and D)

Question 5

______________ markedly stimulates glycogen breakdown in muscle by initiating a cAMP signal-transduction cascade.

Accepted Answer

Epinephrin...

Question 6

The complete oxidation of a glucose residue from glycogen produces ________________ molecules of ATP in the muscle.

Accepted Answer

The answer of The complete oxidation of a glucose residue...

Question 7

What did Carl and Gerti Cori discover about the cause of von Gierke disease? Briefly explain how this information helps to explain the symptoms of the disease.

Accepted Answer

They discovered that the cause of von Gi...

Question 8

What is the activated form of glucose required for glycogen synthesis?

Accepted Answer

A)   glucose-6-phosphate
B)   glucose-1-phosphate
C)   ADP-glucose
D)   UDP-glucose
E)   GDP-glucoseF) None of the above
G) B) and D)

Question 9

Conversion of glucose 1-phosphate to glucose 6-phosphate is carried out by the enzyme

Accepted Answer

A)   phosphoglucomutase.
B)   kinase 1-P.
C)   phosphoglycerate mutase.
D)   hexose-phosphate isomerase.
E)   None of the answers is correct.F) B) and E)
G) A) and B)

Question 10

Phosphoglucomutase requires the intermediate ____________________ for the interconversion of glucose-1-phosphate and glucose-6-phosphate.

Accepted Answer

glucose 1,...

Question 11

What is the primary glycosidic bond found in glycogen?

Accepted Answer

A)    α\alphaα -1,3
B)    α\alphaα -1,4
C)    α\alphaα -1,6
D)    β\betaβ -1,4
E)    β\betaβ -1,6 F) A) and D)
G) B) and E)

Question 12

The key regulatory enzyme that primarily controls the rate of glycogen synthesis is

Accepted Answer

A)   glycogen synthase phosphorylase.
B)   glycogen synthase.
C)   glycogen synthase kinase.
D)   protein phosphatase-1.
E)   None of the answers is correct.F) C) and E)
G) A) and D)

Question 13

The action of which of the following enzymes both activates glycogen breakdown and inhibits glycogen synthesis?

Accepted Answer

A)   protein kinase A
B)   protein kinase C
C)   phosphorylase kinase
D)   protein phosphatase 1
E)   None of the answers is correct.F) C) and D)
G) A) and E)

Question 14

What liver enzyme catalyzes the hydrolysis of a phosphate group to produce glucose?

Accepted Answer

A)   glucose phosphorylase
B)   glucose-1-phosphatase
C)   glucose-4-phosphatase
D)   glucose-6-phosphatase
E)   None of the answers is correct.F) A) and E)
G) A) and D)

Question 15

What path in addition to the cAMP-induced signal transduction is used in the liver to stimulate glycogen breakdown by epinephrine?

Accepted Answer

In the liver, epinephrine also binds to ...

Question 16

By what mechanism is phosphorylase kinase activated by Ca2+ levels of 1 μM?

Accepted Answer

The δ subunit of phosphorylase kinase is...

Question 17

The glycogen branching enzyme moves a block of __________ (or so) glucose residues to form a branch point at least four residues from a preexisting branch.

Accepted Answer

The answer of The glycogen branching enzyme moves a block...

Question 18

In muscle, the first event in the breakdown of glycogen due to binding of a hormone is _____.

Accepted Answer

A)   cytoplasmic cAMP levels rise
B)   protein kinase A phosphorylates phosphorylase kinase
C)   adenylate cyclase is activated
D)   protein kinase A is activated
E)   activation of a G proteinF) D) and E)
G) None of the above

Question 19

Why must glycogen control be manifested differently in muscle and liver?

Accepted Answer

It is because the muscle maint...

Question 20

What are some of the advantages of having glycogen as a glucose source?

Accepted Answer

Glycogen is readily accessible and can b...

Exam 21: Glycogen Metabolism

Phosphoglucomutase requires the intermediate ____________________ for the interconversion of glucose-1-phosphate and glucose-6-phosphate.

Correct Answerverifiedglucose 1,...View AnswerShow Answer

What did Carl and Gerti Cori discover about the cause of von Gierke disease? Briefly explain how this information helps to explain the symptoms of the disease.

Correct AnswerverifiedThey discovered that the cause of von Gi...View AnswerShow Answer

What path in addition to the cAMP-induced signal transduction is used in the liver to stimulate glycogen breakdown by epinephrine?

Correct AnswerverifiedIn the liver, epinephrine also binds to ...View AnswerShow Answer

______________ markedly stimulates glycogen breakdown in muscle by initiating a cAMP signal-transduction cascade.

Correct AnswerverifiedEpinephrin...View AnswerShow Answer

What is the activated form of glucose required for glycogen synthesis?

Correct AnswerverifiedShow Answer

The complete oxidation of a glucose residue from glycogen produces ________________ molecules of ATP in the muscle.

Correct AnswerverifiedShow Answer

What liver enzyme catalyzes the hydrolysis of a phosphate group to produce glucose?

Correct AnswerverifiedShow Answer

Why does liver possess a specific enzyme that can cleave glucose 6-phosphate to form glucose and orthophosphate?

Correct AnswerverifiedThe liver controls the blood g...View AnswerShow Answer

By what mechanism is phosphorylase kinase activated by Ca2+ levels of 1 μM?

Correct AnswerverifiedThe δ subunit of phosphorylase kinase is...View AnswerShow Answer

The action of which of the following enzymes both activates glycogen breakdown and inhibits glycogen synthesis?

Correct AnswerverifiedShow Answer

What is the primary glycosidic bond found in glycogen?

Correct AnswerverifiedShow Answer

What is the function of liver glycogen degradation?

Correct AnswerverifiedShow Answer

What reaction cleaves a bond by the addition of orthophosphate?

Correct AnswerverifiedShow Answer

What are some of the advantages of having glycogen as a glucose source?

Correct AnswerverifiedGlycogen is readily accessible and can b...View AnswerShow Answer

In muscle, the first event in the breakdown of glycogen due to binding of a hormone is _____.

Correct AnswerverifiedShow Answer

Why must glycogen control be manifested differently in muscle and liver?

Correct AnswerverifiedIt is because the muscle maint...View AnswerShow Answer

Conversion of glucose 1-phosphate to glucose 6-phosphate is carried out by the enzyme

Correct AnswerverifiedShow Answer

Glycogen synthase is converted into the active form by the action of _________________.

Correct Answerverifiedprotein ph...View AnswerShow Answer

The glycogen branching enzyme moves a block of __________ (or so) glucose residues to form a branch point at least four residues from a preexisting branch.

Correct AnswerverifiedShow Answer

The key regulatory enzyme that primarily controls the rate of glycogen synthesis is

Correct AnswerverifiedShow Answer

Correct Answer
verified
glucose 1,...
View Answer

Correct Answer
verified
They discovered that the cause of von Gi...
View Answer

Correct Answer
verified
In the liver, epinephrine also binds to ...
View Answer

Correct Answer
verified
Epinephrin...
View Answer

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified
The liver controls the blood g...
View Answer

By what mechanism is phosphorylase kinase activated by Ca²⁺ levels of 1 μM?

Correct Answer
verified
The δ subunit of phosphorylase kinase is...
View Answer

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified
Glycogen is readily accessible and can b...
View Answer

Correct Answer
verified

Correct Answer
verified
It is because the muscle maint...
View Answer

Correct Answer
verified

Correct Answer
verified
protein ph...
View Answer

Correct Answer
verified

Correct Answer
verified