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The X protein from hepatitis B virus is thought to activate gene transcription because it is found in the nucleus of infected cells.

A) True
B) False

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Like retroviruses,hepatitis B virus (HBV) uses a reverse transcription step.Which of the following distinguishes HBV from the retroviruses?


A) HBV has an enveloped virion.
B) HBV packages a DNA genome in the virion.
C) HBV packages reverse transcriptase enzyme in the virion.
D) HBV fuses its envelope with the cellular plasma membrane.
E) All of the above distinguish HBV from retroviruses.

F) C) and D)
G) B) and C)

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Hepatitis B is usually transmitted via the oral-fecal route.

A) True
B) False

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Scientists are currently testing an edible vaccine for hepatitis B virus by engineering the antigens into bananas.

A) True
B) False

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The unusual structure of the of the hepatitis B virus genome found in the virion is a result of the mechanism used to replicate the genome.

A) True
B) False

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It is recommended that people in certain professions or with certain disease should receive the hepatitis B vaccine.For which of the following individuals would it NOT be critical for them to be vaccinated against hepatitis B?


A) Zoo keeper
B) Nurse
C) Tattoo-parlor worker
D) Barber
E) Hemophiliac

F) B) and C)
G) B) and E)

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Like retroviruses,the genome of hepatitis B virus is integrated into the genome of the host cell.

A) True
B) False

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Which of the following describes an interesting feature of the preC and pregenomic mRNAs produced by the hepatitis B virus?


A) They are extensively spliced to produce a set of nested mRNAs.
B) They are transcribed by the cellular RNA polymerase III enzyme.
C) They are produced by the reverse transcriptase enzyme.
D) They are transcribed past a polyadenylation site near the promoter.
E) They each code for several proteins due to the use of alternative start codons.

F) A) and E)
G) A) and D)

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