Question 1

The most significant influence on why mRNA is processed differently in prokaryotes than eukaryotes is the fact that

Accepted Answer

A)   eukaryotes separate transcription and translation with a nucleus.
B)   prokaryotes are often polycistronic.
C)   eukaryotes are multicellular organisms.
D)   prokaryotes do not add a poly(
A)   tail.E) C) and D)
F) A) and B)

Question 2

Which protein-synthesizing RNA molecule carries an amino acid to the ribosome active site?

Accepted Answer

A)   rRNA
B)   tRNA
C)   mRNA
D)   siRNAE) B) and D)
F) A) and B)

Question 3

Eukaryotic RNA polymerase II facilitates the

Accepted Answer

A)   removal of exons.
B)   addition of 7-methylguanylate cap.
C)   addition of a poly(
A)   tail.
D)   translation of the RNA transcript.E) A) and B)
F) B) and C)

Question 4

Which is NOT required in the prokaryotic transcription initiation complex?

Accepted Answer

A)   a primer
B)   RNA polymerase
C)   initiation factor
D)   a ribonucleotide triphosphate (NTP) E) C) and D)
F) None of the above

Question 5

Which of the following is a coding RNA molecule?

Accepted Answer

A)   short interfering RNA.
B)   TERC RNA.
C)   small nucleolar RNA.
D)   messenger RNA.E) C) and D)
F) A) and B)

Question 6

Which type of RNA facilitates RNA interference by resulting in degraded mRNA?

Accepted Answer

A)   snoRNA
B)   siRNA
C)   miRNA
D)   rRNAE) B) and C)
F) All of the above

Question 7

Which RNA molecule does NOT bind to the ribosome?

Accepted Answer

A)   tRNA
B)   rRNA
C)   mRNA
D)   snRNAE) A) and B)
F) B) and D)

Question 8

The picture below shows the TATA binding protein. What is its role?

Accepted Answer

The TATA binding protein is a ...

Question 9

Which RNA molecule is expressed in the genome to regulate gene expression?

Accepted Answer

A)   RNAi
B)   snoRNA
C)   miRNA
D)   siRNAE) C) and D)
F) All of the above

Question 10

Would a weak or a strong promotor be more active in a prokaryotic cell? Explain your answer.

Accepted Answer

It may depend on the organism ...

Question 11

The strand of DNA is transcribed into mRNA.

Accepted Answer

A)   leading
B)   coding
C)   lagging
D)   templateE) A) and B)
F) All of the above

Question 12

Which enzyme degrades the poly(A)  tail in the degradation of mRNA?

Accepted Answer

A)   poly(
A)   binding protein
B)   exosome
C)   CCR4
D)   DCP1 and DCP2E) A) and D)
F) B) and C)

Question 13

Which of the following RNA molecules has the LEAST number of different sequences in a given organism?

Accepted Answer

A)   tRNA
B)   rRNA
C)   mRNA
D)   snRNAE) C) and D)
F) A) and B)

Question 14

It has been estimated that as much as % of the human genome is transcribed into noncoding RNA, whereas % of the E. coli genome is noncoding RNA.

Accepted Answer

A)   10; 90
B)   90; 10
C)   50; 10
D)   25; 2E) A) and B)
F) A) and C)

Question 15

RNA is a dynamic biomolecule because it can

Accepted Answer

A)   be a component in protein synthesis, regulate protein synthesis, and be synthesized and function in cell nucleus.
B)   catalyze its own synthesis.
C)   contain a ribose sugar backbone.
D)   be stable to hydrolysis.E) All of the above
F) None of the above

Question 16

Describe the difference between $\sigma$ factors for housekeeping genes and those for other genes.

Accepted Answer

Housekeeping genes are those that are st...

Question 17

Describe the composition and processing of the C-terminal domain (CTD) of eukaryotic RNA polymerase II, as well as its role in transcription.

Accepted Answer

The CTD is a repeating peptide sequence ...

Question 18

Most post-transcriptional RNA processing reactions are catalyzed by

Accepted Answer

A)   DNAzymes.
B)   ribozymes.
C)   ligases.
D)   transferases.E) A) and D)
F) A) and C)

Question 19

Eukaryotic promoters, but NOT prokaryotic promoters,

Accepted Answer

A)   are located before the transcription start site.
B)   bind transcription factors.
C)   are located after the transcription start site.
D)   assist in activating transcription.E) A) and B)
F) C) and D)

Question 20

Group I and group II introns are similar in their

Accepted Answer

A)   requirement for metal ion cofactors.
B)   requirement for exogenous nucleoside binding.
C)   DNA composition.
D)   intron lariat structure.E) A) and B)
F) B) and C)

Exam 21: RNA Synthesis, Processing, and Gene Silencing

Group I and group II introns are similar in their

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Which enzyme degrades the poly(A) tail in the degradation of mRNA?

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Which protein-synthesizing RNA molecule carries an amino acid to the ribosome active site?

Correct AnswerverifiedShow Answer

Which RNA molecule is expressed in the genome to regulate gene expression?

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Which of the following RNA molecules has the LEAST number of different sequences in a given organism?

Correct AnswerverifiedShow Answer

Describe the composition and processing of the C-terminal domain (CTD) of eukaryotic RNA polymerase II, as well as its role in transcription.

Correct AnswerverifiedThe CTD is a repeating peptide sequence ...View AnswerShow Answer

Describe the difference between σ\sigmaσ factors for housekeeping genes and those for other genes.

Correct AnswerverifiedHousekeeping genes are those that are st...View AnswerShow Answer

It has been estimated that as much as % of the human genome is transcribed into noncoding RNA, whereas % of the E. coli genome is noncoding RNA.

Correct AnswerverifiedShow Answer

RNA is a dynamic biomolecule because it can

Correct AnswerverifiedShow Answer

The picture below shows the TATA binding protein. What is its role?

Correct AnswerverifiedThe TATA binding protein is a ...View AnswerShow Answer

Eukaryotic promoters, but NOT prokaryotic promoters,

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Which type of RNA facilitates RNA interference by resulting in degraded mRNA?

Correct AnswerverifiedShow Answer

Would a weak or a strong promotor be more active in a prokaryotic cell? Explain your answer.

Correct AnswerverifiedIt may depend on the organism ...View AnswerShow Answer

Eukaryotic RNA polymerase II facilitates the

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The most significant influence on why mRNA is processed differently in prokaryotes than eukaryotes is the fact that

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Most post-transcriptional RNA processing reactions are catalyzed by

Correct AnswerverifiedShow Answer

Which RNA molecule does NOT bind to the ribosome?

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Which of the following is a coding RNA molecule?

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Which is NOT required in the prokaryotic transcription initiation complex?

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The strand of DNA is transcribed into mRNA.

Correct AnswerverifiedShow Answer

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The CTD is a repeating peptide sequence ...
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Describe the difference between $\sigma$ factors for housekeeping genes and those for other genes.

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Housekeeping genes are those that are st...
View Answer

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Correct Answer
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Correct Answer
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The TATA binding protein is a ...
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It may depend on the organism ...
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